Activitat científica

Epidemiologia digital i medicina de precisió

• Vela E, Clèries M, Monterde D, Carot-Sans G, Coca M, Valero-Bover D, Piera-Jiménez, J, Eroles L, Pérez Sust P. Performance of Quantitative Measures of Multimorbidity: A Population-Based Retrospective Analysis. BMC Public Health. 2021; 10.21203/rs.3.rs-209438/v1..
• Monterde D, Carot-Sans G, Cainzos-Achirica M, Abilleira S, Coca M, Vela E, Clèries M, Valero-Bover D, Comin-Colet J, García-Eroles L, Pérez-Sust P, Arrufat M, Lejardi Y, Piera-Jiménez J. Performance of three measures of Comorbidity in predicting critical COVID-19: A retrospective analysis of 4607 hospitalized patients. Risk Manag. Healthc. Policy 14, 4729–4737. 2021;.
• Vela E, Carot-Sans G, Clèries M, Monterde D, Acebes X, Comella A, García Eroles L, Coca M, Valero-Bover D, Piera-Jiménez J, Pérez Sust P. Development and validation of a population-based risk stratification model for COVID-19 in the general population. Sci. Rep. 2022; 12, 3277.
• Satish P, Vela E, Bilal U, Cleries M, Kanaya AM, Kandula N, et al. Burden of cardiovascular risk factors and disease in five Asian groups in Catalonia: a disaggregated, population-based analysis of 121 000 first-generation Asian immigrants. Eur J Prev Cardiol. 2021.
• Surís X, Vela E, Clèries M, Pueyo-Sánchez M-J, Llargués E, Larrosa M. Epidemiology of major osteoporotic fractures: a population-based analysis in Catalonia, Spain. Arch Osteoporos. 2022 Dec 10;17(1):47.
• Manchon-Walsh P, Aliste L, Borràs JM, Coll-Ortega C, Casacuberta J, Casanovas-Guitart C, Clèries M, Cruz S, Guarga À, Mompart A, et al. Socioeconomic Status and Distance to Reference Centers for Complex Cancer Diseases: A Source of Health Inequalities? A Population Cohort Study Based on Catalonia. Int. J. Environ. Res. Public Health 2022, 19, 8814.
• Mullachery Pricila H, Vela E, Cleries M, Comin-Colet J, Nasir K, Diez Roux A, Cainzos-Achirica M, Mauri J, Bilal U. Inequalities by income in the prevalence of cardiovascular disease and its risk factors in the adult population of Catalonia. Journal of the American Heart Association 2022. Submitted, in press
• Valero-Bover D, Monterde D, Carot-Sans G, Cainzos-achirica M, Comin-colet J, Vela E, et al. Is Age the Most Important Risk Factor in COVID-19 Patients? The Relevance of Comorbidity Burden: A Retrospective Analysis of. Clin Epidemiol. 2023;(June):811-25
• Cases L, Vela E, Gonzàlez SJS, Contel JC, Carot-Sans G, Coca M, et al. Excess mortality among older adults institutionalized in long-term care facilities during the COVID-19 pandemic: a population-based analysis in Catalonia. Front Public Heal. 2023;11.
• Risco R, González-Colom R, Montané-Muntané M, Cano I, Vela E, Sebio R, et al. Actionable factors fostering health value generation and scalability of prehabilitation: a prospective cohort study. Ann Surg. 2023;278(2):e217��25.
• Aguilera CC, Vallespín EV, Escayola MC, Viladomat SY, Solana CF, Morte LA, et al. Population-based evaluation of the impact of socioeconomic status on clinical outcomes in patients with heart failure in integrated care settings. Rev Española Cardiol (English Ed). 2023.

Desenvolupament, avaluació i implementació de solucions digitals i assistencials per a la millora de la qualitat assistencial i la sostenibilitat del sistema de salut

• Fidel Kinori S, Carot-Sans G, Cuartero A, Valero-Bover D, Piera-Jiménez J, Roma Monfa R, Garcia Ribatallada E, Pérez Sust P, Blanch Andreu J, Ramos-Quiroga J. Web App for Emotional Management During the COVID-19 Pandemic: Platform Development and Retrospective Analysis of Its Use Throughout Two Waves of the Outbreak in Spain. JMIR Formative Research, 2021.
• Valero-Bover D, González P, Carot-Sans G, Cano I, Saura P, Otermin P, et al. Reducing non-attendance in outpatient appointments: predictive model development, validation, and clinical assessment. BMC Health Serv Res. 2022 Dec 6;22(1):451.
• Vela E, Plaza A, Carot-Sans G, Contel JC, Salvat-Plana M, Fabà M, et al. Data and care integration for post-acute intensive care program of stroke patients: effectiveness assessment using a disease-matched comparator cohort. J Int care. 2022. (Accepted, in press).
• Solans O, Vidal-Alaball J, Roig Cabo P, Mora N, Coma E, Bonet Simó JM, Hermosilla Pérez E, Saigí-Rubió F, Holmos C, Piera-Jiménez J, et al. Characteristics of citizens and their use of teleconsultation in Primary Care in the Catalan public health system before and during COVID: Retrospective Descriptive Cross-Sectional Study. JMIR Prepr. 2021;28629.
• Saigí-Rubió F, Vidal-Alaball J, Torrent-Sellens J, Jiménez-Zarco A, Segui FL, Hernandez MC, et al. Determinants of Catalan public primary care professionals’ intention to use digital clinical consultations (eConsulta) in the Post-COVID-19 context: mixed methods study. JMIR. 2021; 23(6), e28944.
• Vis C, Schuurmans J, Aouizerate B, Atipei Craggs M, Batterham P, Bührmann L, et al. Effectiveness of self-guided tailored implementation strategies in integrating and embedding internet-based cognitive behavioral therapy in routine mental health care: results of a multicenter stepped-wedge cluster randomized trial. J Med Internet Res. 2023;25:e41532.
• Tarp K, Nielsen SL, Holmberg TT, Dalsgaard CH, Borkner S, Skaarnes H, et al. Therapist perceptions of the implementation of a new screening procedure using the ItFits-toolkit in an iCBT routine care clinic: A mixed-methods study using the consolidated framework for implementation research. Front Psychiatry. 2023;14:1104301.
• Risco R, González-Colom R, Montané-Muntané M, Cano I, Vela E, Sebio R, et al. Actionable factors fostering health value generation and scalability of prehabilitation: a prospective cohort study. Ann Surg. 2023;278(2):e217.

Ús racional del medicament i millora de les prestacions farmacèutiques

• Guarga L, Paco N, Vela E, Clèries M, Corral J, Delgadillo J, Pontes C, Borràs JM. Changes in Treatment Patterns and Costs for Lung Cancer Have Not Resulted in Relevant Improvements in Survival: A Population-Based Observational Study in Catalonia. Cancers (Basel). 2022;14(23):5791.
• Gasol M, Paco N, Guarga L, Bosch JÀ, Pontes C, Obach M. Early Access to Medicines: Use of Multicriteria Decision Analysis (MCDA) as a Decision Tool in Catalonia (Spain). J. Clin. Med. 2022.
• Brunet E, Vela E, Melcarne L, Llovet L, Puy A, Pontes C, et al. Heterogeneity in pharmacological treatment and outcomes in Crohn’s diseade patients in Catalonia: a population-based observational study. Ann Med. 2022;54(1):1255-64.
• Pisana A, Wettermark B, Kurdi A, Tubic B, Pontes C, Zara C, Van Ganse E, Petrova G, Mardare I, Fürst J, Roig-Izquierdo M, Melien O, Bonanno PV, Banzi R, Marković-Peković V, Mitkova Z, Godman B. Challenges and Opportunities With Routinely Collected Data on the Utilization of Cancer Medicines. Perspectives From Health Authority Personnel Across 18 European Countries. Front Pharmacol. 2022 Jun 16;13:873556.
• Solís-Díez G, Turu-Pedrola M, Roig-Izquierdo M, Zara C, Vallano A, Pontes C. Dealing With Immunoglobulin Shortages: A Rationalization Plan From Evidence.Based and Data Collection. Front Public Health. 2022 May 19;10:893770.
• Selke Krulichová I, Selke GW, Bennie M, Hajiebrahimi M, Nyberg F, Fürst J, Garuolienė K, Poluzz, E, Slabý J, Yahni CZ, Altini M, Fantini MP, Kočí V, McTaggart S, Pontes C, Reno C, Rosa S, Pedrola MT, Udovič M & Wettermark B. Comparison of drug prescribing before and during the COVID-19 pandemic: A cross-national European study. Pharmacoepidemiol Drug Saf. 2022 Jul 6.
• Vivanco-Hidalgo RM, Molina I, Martinez E, Roman-Viñas R, Sánchez-Montalvá A, Fibla J, Pontes C, Velasco Muñoz C. Incidence of COVID-19 in patients exposed to chloroquine and hydroxychloroquine: results from a population-based prospective cohort in Catalonia, Spain, 2020. Euro Surveill. 2021 Mar;26(9).
• Guarga L, Paco N, Manchon-Walsh P, Vela E, Delgadillo J, Pontes C, et al. Management, Survival, and Costs of Pancreatic Cancer: Population-Based Observational Study in Catalonia. Int J Environ Res Public Health. 2023;20(9):5673.
• Pesiou S, Barcelo R, Fradera M, Torres F, Pontes C. Utilisation of drugs for the treatment of psychiatric diseases in the pediatric population: focus on off-label use. Front Pharmacol. 2023;14:1157135.
• Elvira D, Torres F, Vives R, Puig G, Obach M, Gay D, Varón D, de Pando T, Tabernero J, Pontes C. Reporting reimbursement price decisions for onco-hematology drugs in Spain. Front Public Health. 2023;11:1265323.
• Vallano A, Pontes C, Agustí A. The challenges of access to innovative medicines with limited evidence in the European Union. Front Pharmacol. 2023;14:1215431.

Al llarg dels primers anys de funcionament, DS3 ha format part de diversos projectes competitius guanyadors, tant en convocatòries nacionals com internacionals.  Els projectes concedits s’esmenten a continuació.

• BEAMER "Behavioral  and  Adherence  Model  for  improving  quality,  health  outcomes and cost - Effectiveness of healthcaRe” (2021 - 2025).  
  IMI Call 23 - Topic 6 - Innovative Medicines Initiative - Horizon 2020
• AI supported image analysis in large bowel camera capsule endoscopy (AICE)
  HORIZON - HLTH - 2021 - DISEASE - 04 - 01 - Clinical validation  of  artificial  intelligence (AI) solutions for treatment and care.
• Ensayo Clínico  abierto  y  Aleatorizado  para  valorar  la  Seguridad  de  la  Teleconsulta, frente a la consulta clínica tradicional (ECASeT)
  Fondo de Investigación Sanitaria - Proyectos de Investigación en Salud (ISCIII).
• Evaluación de una estrategia de intervención para la mejora de la adherencia en la terapia endocrina en mujeres con cáncer de mama basada en datos del sistema sanitario en Cataluña
  PI21/00687 - Instituto de Salud Carlos III. Convocatoria 2021 de la Acción estratégica en salud 2017 – 20.
• HI - PR IX project   (HEALTH   INNOVATION   NEXT   GENERATION   PRICING   MODELs): Balancing Sustainability of Innovation with Sustainability of Health Care
  HORIZON - HLTH - 2022 - IND - 13 - 03 - New pricing and payment models  for  cost-effective and affordable health innovations.
• Coordination and data federation for distributed analytics (dataFED)
  Ministerio de Ciencia e Innovación - PROYECTOS DE  TRANSICIÓN  ECOLÓGICA  Y TRANSICIÓN DIGITAL 2021.
• Towards large - scale adaptation and tailored implementation  of  evidence - based primary cancer prevention programmes in Europe and beyond (PIECES)
  HORIZON - MISS - 2022 - CANCER - 01 - 01- Research and Innovation actions supporting the implementation of the Mission on Cancer.
• Framework to IMPROVE the Integration of Patient Generated Health Data to Facilitate Value Based Healthcare (IMPROVE)
  HORIZON - JU - IHI - 2022 - 03 – 02 - Patient - generated evidence   to   improve   outcomes, support decision making, and accelerate innovation.
• Modelling and dynamic assessment of integrated health and care pathways enhancing response capacity of health systems (DYNAMO)
  HORIZON - HLTH - 2022 - CARE - 08 – 02 - Ensuring access to innovative, sustainable and high-quality health care.